A smart insulin discovery endeavour
Insulin that
switches off
before glucose
goes low.
Rethinking the dose-limiting problem in insulin therapy.
Contact DIA HEALTH ONE ↗A safer glucose response
CONCEPT
GLUCOSE LEVELTIME →
glucose responsesmart insulin
Responsive by design ↗
01 — DISCOVERY
01 / The need
Why we
need it.
Hypoglycemia is insulin’s dose-limiting problem.
Not a side effect.
The ceiling.
02 / The gap
Why is it
not fixed?
“Novo’s NNC2215 almost worked — but a simple paracetamol glucuronide corrupted it.
Patients under-dose, and therefore, chronic hyperglycemia is the price.
03 / The approach
Compute.
Falsify.
Discover.
We compute the target, then falsify mechanisms analytically.
Each hypothesis is tested in days, not years.
TargetMechanismEvidence